Introducing the Future of Organ Preservation

Redefining what’s possible in donor heart transport
Vascular Perfusion Solutions is advancing organ transplantation with VP.S ENCORE®, a premarket cardiac perfusion system designed to extend donor heart viability up to eight hours.

Saving Organs. Saving Lives.

Built to address the limitations of conventional cold storage, VP.S ENCORE® represents a new approach to heart preservation technology, operating without blood or blood products and using using FDA-cleared perfusate.

VP.S ENCORE®
Donor Heart Preservation

Designed to support donor heart preservation for up to 8 hours.

More than 100,000 patients are awaiting transplant, yet standard cold storage preserves donor hearts for only up to 4-6 hours. As a result, only 40% of available donor hearts are transplanted. VP.S ENCORE® is designed to extend donor heart viability, limit ischemic injury, and support flexible timing and logistics during organ recovery and transport.

VP.S ENCORE®: Engineered for Simplicity

VP.S ENCORE® has undergone extensive preclinical evaluation, including more than 100 heart perfusions, and has received FDA Breakthrough Device Designation.
VP.S ENCORE®

Simple

Designed to streamline workflows using familiar, standardized materials while eliminating system components that can delay or complicate setup.

Doctor carrying the VP.S ENCORE®

Portable

Compact, built for single-person handling, and powered by a long-lasting battery, VP.S ENCORE® supports uninterrupted preservation without relying on specialized transport or additional staff.

VP.S ENCORE®

Reliable

Features a built-in cold storage fallback to protect the organ if circulation is interrupted, helping maintain hypothermic conditions while minimizing ischemic risk across longer distances.

Built for the Demands of Transplant Care

For Cardiac Surgeons
VP.S ENCORE® is being developed to address the limits of current preservation methods by supporting donor heart viability during transport and extending the window beyond standard cold storage.
For OPO Teams
OPOs face rigorous outcome measures tied to donation rates, organ utilization, and timely transplant performance. VP.S ENCORE® supports these demands with a portable, bloodless system to help reduce transport constraints, streamline recovery logistics, and expand access to viable donor hearts.

VPS Insights

Explore publications, scientific data, and supporting resources that offer a closer look at hypothermic perfusion, organ preservation technology, and the broader VP.S ENCORE® research platform.

VPS Insights

Explore publications, scientific data, and supporting resources that offer a closer look at hypothermic perfusion, organ preservation technology, and the broader VP.S ENCORE® research platform.

The Organ Preservation TEMPest: The Hypothermic vs. Normothermic Turmoil in the Organ Perfusion Industry

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Academic Collaborations and Research Initiatives

Vascular Perfusion Solutions is advancing research initiatives in collaboration with leading cardiac centers, government institutions, and more.

Ongoing work includes organ preservation science, pediatric heart preservation, kidney preservation, gene delivery during perfusion, and vascularized composite tissue preservation.

The University of Texas San Antonio logo
University of Nebraska Medical Center logo
Duke University logo
Wyss Institute logo
The Texas Heart Institute Center for Cardiovascular Care logo

See What’s Next in Donor Heart Preservation

Connect with our team to learn more about VP.S ENCORE® and explore the technology in development.

See What’s Next in Donor Heart Preservation

Connect with our team to learn more about VP.S ENCORE® and explore the technology in development.
VP.S ENCORE®

About Vascular Perfusion Solutions

Vascular Perfusion Solutions is a Texas-based MedTech company focused on advancing cardiac graft preservation through simplified hypothermic machine perfusion technology. The company takes a data-driven, evidence-based approach to research and development, working closely with leading scientists, engineers, and industry advisors to rigorously evaluate and refine its technology.

Its flagship system, VP.S ENCORE®, reflects this commitment to scientific integrity and practical innovation in cardiac transplantation.