Vascular Perfusion Solutions | Saving Organs. Limbs. Lives.

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WHAT IF...

More organs are made available?

Transplant Surgeons

Surgeons will be able to serve more patients while streamlining their practices and better managing their personal lives.

OPOs

Organ Procurement Organizations will have greater access to quality organs, helping them meet expanding federal requirements

The Problem

These numbers are a painful reminder that a solution must be found for those donating and receiving life-saving organs. This is why the Vascular Perfusion Solutions team is committed to delivering a solution that will save organs and lives!

THE SOLUTION :

The VP.S ENCORE™ Device is designed to extend the viability of organs outside the body beyond the current standard of care (SOC) which uses ice cooling.

The VP.S ENCORE™ Device, with patents pending, has received a Breakthrough Device Designation from the FDA. The Breakthrough Device Designation is designed to facilitate communications between the company and the FDA to ideally accelerate the device to market.

The VP.S ENCORE™ is a device that can be modified to eventually extend the preservation of other organs and vascularized tissue. Future uses include the use of ex vivo therapies, and ideally provide a foundation for organ banking.

The impact in developing the VP.S ENCORE™ device promises to be significant once data are gathered to demonstrate that this technology can expand the donor pool, resulting in optimized organ matching with less rejection such as primary graft dysfunction.

VIABLE HEARTS

Preclinical testing using ex vivo human and porcine organs demonstrated favorable results when the VP.S ENCORE™ device was directly compared against the SOC control device (ice cooler). Assessments of tissue viability including parameters such as lactate reduction, enhanced contractility, reduced inflammation, and cell death were compared for the VP.S ENCORE™ device versus the SOC ice cooler method. The preclinical results suggest the VP.S ENCORE™ device resulted in superior performance compared to the current SOC in all tests that compared tissue viability after preservation.

PORTABLE

The VP.S ENCORE™ Device is designed to facilitate transportation with an outer housing the size of carry-on luggage. By comparison, competing technologies that utilize blood as the perfusate are large and cumbersome requiring special transport vehicles.

EASE OF USE

The VP.S ENCORE™ system includes a single-use disposable component that operates with a non-blood, nutrient-rich solution (perfusate) that is available in transplant centers. The system is designed to operate in environments with temperatures up to 40 C and to withstand passenger aircraft cabin pressures.

In addition, the VP.S ENCORE™ device has a rugged design that is easy to transport, and should the device fail for any reason, the device reverts to the standard of care (static cooling).

SEE THE DIFFERENCE

Human Heart

24-hour Porcine Heart